With rookie quarterback Skylar Thompson at the helm for their Week 18 game against the New York Jets, the Miami Dolphins will likely need to prevail.
The opposing Miami Dolphins team will also start a different quarterback.
Mike White's rib ailment has caused the Jets to rule him out of the game on Sunday.
To lead the attack, New York is instead relying on shrewd veteran Joe Flacco.
Zach Wilson started their season-opening battle, which the Jets won, before being replaced by White on the bench.
Flacco now seeks to terminate the Dolphins' campaign.
Last season, Miami played a Flacco-led Jets squad.
The Dolphins prevailed 24-17 in the game.
But Flacco finished the game with a passer rating of 101.5 after completing 61.5% of his throws for 291 yards and two touchdowns.
The Dolphins' defence, which hasn't been great this season, can't unwind just because of this alteration.
They will still need to remain focused and give it their all to prevail.